The Three Mouse Actin-depolymerizing Factor/Cofilins Evolved to Fulfill Cell-Type–specific Requirements for Actin Dynamics
نویسندگان
چکیده
منابع مشابه
The three mouse ADF / cofilins evolved to fulfill cell - type specific requirements for actin dynamics
ADF/cofilins are essential regulators of actin filament turnover. Several ADF/cofilin isoforms are found in multicellular organisms, but their biological differences have remained unclear. Here we show that three ADF/cofilins exist in mouse and most likely in all other mammalian species. Northern blot, and in situ hybridization analyses demonstrate that cofilin-1 is expressed in most cell types...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2002
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.01-07-0331